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Table 3 Estimates of the effect of the intervention on the prescribing of antidepressants assuming a constant difference between intervention and control practices in the year following the intervention

From: Is untargeted educational outreach visiting delivered by pharmaceutical advisers effective in primary care? A pragmatic randomized controlled trial

Drug   Average change per quarter across six quarters and all practices Mean (95% CI) difference between intervention and control practices
Tricyclic antidepressants (excluding lofepramine) Items/ASTRO PU 0.00 (-0.04, 0.04) 0.02 (-0.42, 0.46)
  Cost (£)/ASTRO PU -0.28 (-0.44, -0.12) 1.18 (0.03, 2.33)
lofepramine Items/ASTRO PU -0.01 (-0.03, 0.00) -0.02 (-0.11, 0.16)
  Cost (£)/ASTRO PU -0.23 (-0.34, -0.12) 0.31 (-0.82, 1.45)
Selective serotonin re-uptake inhibitors Items/ASTRO PU 0.27 (0.24, 0.30) -0.03 (-0.34, 0.27)
  Cost (£)/ASTRO PU -5.92 (-6.89, 4.95) 0.66 (-6.61, 7.94)
Monoamine oxidase inhinitors Items/ASTRO PU -0.004 (-0.006, -0.002) 0.00 (-0.02, 0.02)
  Cost (£)/ASTRO PU -0.08 (-0.11, -0.04) 0.10 (-0.15, 0.35)