Table 3 Estimates of the effect of the intervention on the prescribing of antidepressants assuming a constant difference between intervention and control practices in the year following the intervention
Drug | Â | Average change per quarter across six quarters and all practices | Mean (95% CI) difference between intervention and control practices |
|---|---|---|---|
Tricyclic antidepressants (excluding lofepramine) | Items/ASTRO PU | 0.00 (-0.04, 0.04) | 0.02 (-0.42, 0.46) |
|  | Cost (£)/ASTRO PU | -0.28 (-0.44, -0.12) | 1.18 (0.03, 2.33) |
lofepramine | Items/ASTRO PU | -0.01 (-0.03, 0.00) | -0.02 (-0.11, 0.16) |
|  | Cost (£)/ASTRO PU | -0.23 (-0.34, -0.12) | 0.31 (-0.82, 1.45) |
Selective serotonin re-uptake inhibitors | Items/ASTRO PU | 0.27 (0.24, 0.30) | -0.03 (-0.34, 0.27) |
|  | Cost (£)/ASTRO PU | -5.92 (-6.89, 4.95) | 0.66 (-6.61, 7.94) |
Monoamine oxidase inhinitors | Items/ASTRO PU | -0.004 (-0.006, -0.002) | 0.00 (-0.02, 0.02) |
|  | Cost (£)/ASTRO PU | -0.08 (-0.11, -0.04) | 0.10 (-0.15, 0.35) |