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  1. Methodology

    Using the Consolidated Framework for Implementation Research (CFIR) to produce actionable findings: a rapid-cycle evaluation approach to improving implementation

    Much research does not address the practical needs of stakeholders responsible for introducing health care delivery interventions into organizations working to achieve better outcomes. In this article, we pres...

    Rosalind E. Keith, Jesse C. Crosson, Ann S. O’Malley, DeAnn Cromp and Erin Fries Taylor

    Implementation Science 2017 12:15

    Published on: 10 February 2017

  2. Research

    Multi-year school-based implementation and student outcomes of an evidence-based risk reduction intervention

    Intervention effects observed in efficacy trials are rarely replicated when the interventions are broadly disseminated, underscoring the need for more information about factors influencing real-life implementa...

    Bo Wang, Bonita Stanton, Lynette Deveaux, Sonja Lunn, Glenda Rolle, Richard Adderley, Maxwell Poitier, Veronica Koci, Sharon Marshall and Perry Gomez

    Implementation Science 2017 12:16

    Published on: 10 February 2017

  3. Editorial

    Enhancing the reporting of implementation research

    In the 10 years since the inception of Implementation Science, we have witnessed a continued rise in the number of submissions received, reflecting the continued global interest in methods to enhance the uptake o...

    Paul M. Wilson, Anne Sales, Michel Wensing, Gregory A. Aarons, Signe Flottorp, Liz Glidewell, Alison Hutchinson, Justin Presseau, Anne Rogers, Nick Sevdalis, Janet Squires and Sharon Straus

    Implementation Science 2017 12:13

    Published on: 8 February 2017

  4. Study protocol

    Integrated solutions for sustainable fall prevention in primary care, the iSOLVE project: a type 2 hybrid effectiveness-implementation design

    Despite strong evidence giving guidance for effective fall prevention interventions in community-residing older people, there is currently no clear model for engaging general medical practitioners in fall prev...

    Lindy Clemson, Lynette Mackenzie, Chris Roberts, Roslyn Poulos, Amy Tan, Meryl Lovarini, Cathie Sherrington, Judy M. Simpson, Karen Willis, Mary Lam, Anne Tiedemann, Dimity Pond, David Peiris, Sarah Hilmer, Sabrina Winona Pit, Kirsten Howard…

    Implementation Science 2017 12:12

    Published on: 7 February 2017

  5. Research

    Pathways for best practice diffusion: the structure of informal relationships in Canada’s long-term care sector

    Initiatives to accelerate the adoption and implementation of evidence-based practices benefit from an association with influential individuals and organizations. When opinion leaders advocate or adopt a best p...

    James W. Dearing, Amanda M. Beacom, Stephanie A. Chamberlain, Jingbo Meng, Whitney B. Berta, Janice M. Keefe, Janet E. Squires, Malcolm B. Doupe, Deanne Taylor, Robert Colin Reid, Heather Cook, Greta G. Cummings, Jennifer L. Baumbusch, Jennifer Knopp-Sihota, Peter G. Norton and Carole A. Estabrooks

    Implementation Science 2017 12:11

    Published on: 3 February 2017

  6. Research

    Understanding causal pathways within health systems policy evaluation through mediation analysis: an application to payment for performance (P4P) in Tanzania

    The evaluation of payment for performance (P4P) programmes has focused mainly on understanding contributions to health service coverage, without unpacking causal mechanisms. The overall aim of the paper is to ...

    Laura Anselmi, Peter Binyaruka and Josephine Borghi

    Implementation Science 2017 12:10

    Published on: 2 February 2017

  7. Study protocol

    Evaluation of the Tsima community mobilization intervention to improve engagement in HIV testing and care in South Africa: study protocol for a cluster randomized trial

    HIV transmission can be decreased substantially by reducing the burden of undiagnosed HIV infection and expanding early and consistent use of antiretroviral therapy (ART). Treatment as prevention (TasP) has be...

    Sheri A. Lippman, Audrey Pettifor, Dumisani Rebombo, Aimée Julien, Ryan G. Wagner, Mi-Suk Kang Dufour, Chodziwadziwa Whiteson Kabudula, Torsten B. Neilands, Rhian Twine, Ann Gottert, F. Xavier Gómez-Olivé, Stephen M. Tollman, Ian Sanne, Dean Peacock and Kathleen Kahn

    Implementation Science 2017 12:9

    Published on: 17 January 2017

  8. Research

    Impact of a tailored program on the implementation of evidence-based recommendations for multimorbid patients with polypharmacy in primary care practices—results of a cluster-randomized controlled trial

    Multimorbid patients receiving polypharmacy represent a growing population at high risk for negative health outcomes. Tailoring is an approach of systematic intervention development taking account of previousl...

    Cornelia Jäger, Tobias Freund, Jost Steinhäuser, Christian Stock, Johannes Krisam, Petra Kaufmann-Kolle, Michel Wensing and Joachim Szecsenyi

    Implementation Science 2017 12:8

    Published on: 13 January 2017

  9. Research

    Multi-strategic intervention to enhance implementation of healthy canteen policy: a randomised controlled trial

    Internationally, governments have implemented school-based nutrition policies to restrict the availability of unhealthy foods from sale. The aim of the trial was to assess the effectiveness of a multi-strategi...

    Luke Wolfenden, Nicole Nathan, Lisa M. Janssen, John Wiggers, Kathryn Reilly, Tessa Delaney, Christopher M. Williams, Colin Bell, Rebecca Wyse, Rachel Sutherland, Libby Campbell, Christophe Lecathelinais, Chris Oldmeadow, Megan Freund and Sze Lin Yoong

    Implementation Science 2017 12:6

    Published on: 11 January 2017

  10. Research

    Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: active and less active ingredients of a multi-component complex intervention to reduce high-risk primary care prescribing

    Two to 4% of emergency hospital admissions are caused by preventable adverse drug events. The estimated costs of such avoidable admissions in England were £530 million in 2015. The data-driven quality improvem...

    Aileen Grant, Tobias Dreischulte and Bruce Guthrie

    Implementation Science 2017 12:4

    Published on: 7 January 2017

  11. Systematic review

    Combined use of the Consolidated Framework for Implementation Research (CFIR) and the Theoretical Domains Framework (TDF): a systematic review

    Over 60 implementation frameworks exist. Using multiple frameworks may help researchers to address multiple study purposes, levels, and degrees of theoretical heritage and operationalizability; however, using ...

    Sarah A. Birken, Byron J. Powell, Justin Presseau, M. Alexis Kirk, Fabiana Lorencatto, Natalie J. Gould, Christopher M. Shea, Bryan J. Weiner, Jill J. Francis, Yan Yu, Emily Haines and Laura J. Damschroder

    Implementation Science 2017 12:2

    Published on: 5 January 2017

  12. Systematic review

    Behavior change interventions and policies influencing primary healthcare professionals’ practice—an overview of reviews

    There is a plethora of interventions and policies aimed at changing practice habits of primary healthcare professionals, but it is unclear which are the most appropriate, sustainable, and effective. We aimed t...

    Bhupendrasinh F. Chauhan, Maya Jeyaraman, Amrinder Singh Mann, Justin Lys, Becky Skidmore, Kathryn M. Sibley, Ahmed Abou-Setta and Ryan Zarychanksi

    Implementation Science 2017 12:3

    Published on: 5 January 2017

    The Erratum to this article has been published in Implementation Science 2017 12:38

  13. Study protocol

    A multidimensional approach to assessing intervention fidelity in a process evaluation of audit and feedback interventions to reduce unnecessary blood transfusions: a study protocol

    In England, NHS Blood and Transplant conducts national audits of transfusion and provides feedback to hospitals to promote evidence-based practice. Audits demonstrate 20% of transfusions fall outside guideline...

    Fabiana Lorencatto, Natalie J. Gould, Stephen A. McIntyre, Camilla During, Jon Bird, Rebecca Walwyn, Robert Cicero, Liz Glidewell, Suzanne Hartley, Simon J. Stanworth, Robbie Foy, Jeremy M. Grimshaw, Susan Michie and Jill J. Francis

    Implementation Science 2016 11:163

    Published on: 12 December 2016

  14. Research

    Effect of a web-based audit and feedback intervention with outreach visits on the clinical performance of multidisciplinary teams: a cluster-randomized trial in cardiac rehabilitation

    The objective of this study was to assess the effect of a web-based audit and feedback (A&F) intervention with outreach visits to support decision-making by multidisciplinary teams.

    Wouter T. Gude, Mariëtte M. van Engen-Verheul, Sabine N. van der Veer, Hareld M. C. Kemps, Monique W. M. Jaspers, Nicolette F. de Keizer and Niels Peek

    Implementation Science 2016 11:160

    Published on: 9 December 2016

  15. Systematic review

    The effectiveness of evidence summaries on health policymakers and health system managers use of evidence from systematic reviews: a systematic review

    Systematic reviews are important for decision makers. They offer many potential benefits but are often written in technical language, are too long, and do not contain contextual details which make them hard to...

    Jennifer Petkovic, Vivian Welch, Maria Helena Jacob, Manosila Yoganathan, Ana Patricia Ayala, Heather Cunningham and Peter Tugwell

    Implementation Science 2016 11:162

    Published on: 9 December 2016

  16. Debate

    Developing the ethics of implementation research in health

    Implementation research (IR) is growing in recognition as an important generator of practical knowledge that can be translated into health policy. With its aim to answer questions about how to improve access t...

    Vijayaprasad Gopichandran, Valerie A. Luyckx, Nikola Biller-Andorno, Amy Fairchild, Jerome Singh, Nhan Tran, Abha Saxena, Pascal Launois, Andreas Reis, Dermot Maher and Mahnaz Vahedi

    Implementation Science 2016 11:161

    Published on: 9 December 2016

  17. Study protocol

    Improving stroke prevention therapy for patients with atrial fibrillation in primary care: protocol for a pragmatic, cluster-randomized trial

    The prevalence of atrial fibrillation (AF) is growing as the population ages, and at least 15% of ischemic strokes are attributed to AF. However, many high-risk AF patients are not offered guideline-recommende...

    Theresa M. Lee, Noah M. Ivers, Sacha Bhatia, Debra A. Butt, Paul Dorian, Liisa Jaakkimainen, Kori Leblanc, Dan Legge, Dante Morra, Alissia Valentinis, Laura Wing, Jacqueline Young and Karen Tu

    Implementation Science 2016 11:159

    Published on: 3 December 2016

  18. Research

    Implementation of the BETTER 2 program: a qualitative study exploring barriers and facilitators of a novel way to improve chronic disease prevention and screening in primary care

    BETTER (Building on Existing Tools to Improve Chronic Disease Prevention and Screening in Primary Care) is a patient-based intervention to improve chronic disease prevention and screening (CDPS) for cardiovasc...

    Nicolette Sopcak, Carolina Aguilar, Mary Ann O’Brien, Candace Nykiforuk, Kris Aubrey-Bassler, Richard Cullen, Eva Grunfeld and Donna Patricia Manca

    Implementation Science 2016 11:158

    Published on: 1 December 2016

  19. Systematic review

    Identifying the barriers and enablers for a triage, treatment, and transfer clinical intervention to manage acute stroke patients in the emergency department: a systematic review using the theoretical domains framework (TDF)

    Clinical guidelines recommend that assessment and management of patients with stroke commences early including in emergency departments (ED). To inform the development of an implementation intervention targete...

    Louise E. Craig, Elizabeth McInnes, Natalie Taylor, Rohan Grimley, Dominique A. Cadilhac, Julie Considine and Sandy Middleton

    Implementation Science 2016 11:157

    Published on: 28 November 2016

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