Much has been written about how the medical home model can enhance patient-centeredness, care continuity, and follow-up, but few comprehensive aids or resources exist to help practices accomplish these aims. The complexity of primary care can overwhelm those concerned with quality improvement.
The RE-AIM planning and evaluation model was used to develop a multimedia, multiple-health behavior tool with psychosocial assessment and feedback features to facilitate and guide patient-centered communication, care, and follow-up related to prevention and self-management of the most common adult chronic illnesses seen in primary care.
The Connection to Health Patient Self-Management System, a web-based patient assessment and support resource, was developed using the RE-AIM factors of reach (e.g., allowing input and output via choice of different modalities), effectiveness (e.g., using evidence-based intervention strategies), adoption (e.g., assistance in integrating the system into practice workflows and permitting customization of the website and feedback materials by practice teams), implementation (e.g., identifying and targeting actionable priority behavioral and psychosocial issues for patients and teams), and maintenance/sustainability (e.g., integration with current National Committee for Quality Assurance recommendations and clinical pathways of care). Connection to Health can work on a variety of input and output platforms, and assesses and provides feedback on multiple health behaviors and multiple chronic conditions frequently managed in adult primary care. As such, it should help to make patient-healthcare team encounters more informed and patient-centered. Formative research with clinicians indicated that the program addressed a number of practical concerns and they appreciated the flexibility and how the Connection to Health program could be customized to their office.
This primary care practice tool based on an implementation science model has the potential to guide patients to more healthful behaviors and improved self-management of chronic conditions, while fostering effective and efficient communication between patients and their healthcare team. RE-AIM and similar models can help clinicians and media developers create practical products more likely to be widely adopted, feasible in busy medical practices, and able to produce public health impact.
The Institute of Medicine  outlined six criteria as the basis for preventive and chronic disease care: patient centered, effective, safe, timely, efficient, and equitable. One way of achieving these aims in primary care is by implementing the core criteria of the Patient-Centered Medical Home (PCMH), which has gained considerable traction as an important part of healthcare reform [2–4].
Achieving the aims of the PCMH, however, can be challenging due to the complexity and multiple competing demands on primary care. The PCMH model includes an emphasis on patient self-management support strategies that provide patients with the information, tools, and support they need to adopt healthy behaviors and take care of their health problems in their daily lives. However, primary care clinicians and staff often lack training in identifying and addressing health behavior and self-management support issues. Stange et al.  concluded that the average amount of time that primary care physicians can devote to prevention in a typical visit is one minute. Data documenting the routine adoption of these changes into primary care practice have been disappointing [6–17]; a large chasm remains between what is possible and what has been achieved . To address this challenge, we describe an approach based on interactive behavior change technology (IBCT) as a vehicle for facilitating the adoption of PCMH strategies into primary care. The reach, effectiveness, adoption, implementation, maintenance/sustainability (RE-AIM) model [18, 19] was used to develop the IBCT program to enhance its chances of successful adoption, implementation, and sustainability in primary care.
Addressing primary care challenges
IBCT can provide efficient methods for achieving the goals of the PCMH. In a review of the literature, members of our team concluded that 'if constructed to draw on the strengths of primary care and to use patient-centered principles, IBCT can inform, leverage, and support patient-provider communication and enhance behavior change .' Integration of self-management support, a major component of the PCMH, into primary care practices can be facilitated through an easy-to-use, time-efficient IBCT system that addresses the most important, behavioral, and psychosocial challenges, especially if focused on the needs of patients with the most common chronic conditions.
The major goals of IBCT, which fit well with PCMH, are to: detect and then monitor patient needs for self-management support over time; prompt clinician/patient discussions to engage patients in behavior change; establish individualized priorities for identified problems; provide guidance and options for intervention at the point of care; and monitor success over time and prompt follow-ups [20, 21]. However, to our knowledge no comprehensive system exists that includes prevention and multiple chronic disease monitoring and intervention that is based on practical, well-documented measures and directly tied to actionable resources and recommendations for clinicians and patients [22–32]. To date, IBCTs have not been widely adopted in real world primary care settings. We posit that one of the reasons for this may be that implementation science concerns and approaches like RE-AIM have not been integrated into the development and testing of the majority of IBCTs. In this article, we summarize key points of the RE-AIM implementation science model, and then describe how it was used to develop an IBCT for the PCMH [33, 34].
The purposes of this article are to: describe the characteristics and design of the IBCT-based Connection to Health self-management support system to support the PCMH; illustrate the use of the RE-AIM model to guide development of Connection to Health; present qualitative results from a focus group discussion of Connection to Health with clinicians and staff members; and discuss practical implications and directions for future research and practice.
RE-AIM planning and evaluation framework
RE-AIM was developed to help health planners and evaluators to attend to specific implementation factors essential for success in the real and complex world of healthcare and community settings [18, 34]. It is an acronym that focuses attention on five key issues related to successful impact and can help design interventions that can: reach a broad and representative proportion of the target population; effectively lead to positive changes in patient self-management and quality of life that are robust across diverse groups; be adopted across a broad and representative proportion of settings; lead to consistent implementation of strategies at a reasonable cost; and lead to maintained self-management in patients and sustained delivery within primary care clinics [19, 35, 36].
RE-AIM can be a valuable planning tool for implementing self-management support and IBCT programs, especially considering the Institute of Medicine aims to provide efficient, patient-centered, equitable care and reduce health disparities. For example, a focus on the representativeness (i.e., reach) of those who engage with the technology and the robustness of the program's effect is critical. With this in mind, developers of an IBCT for self-management support should design features to ensure that appropriate audio and visual aids are in place to assist all patients, particularly low literacy, minority, less acculturated, older, poorer, or less educated patients who may feel overwhelmed with the healthcare system and confused by complex forms and procedures.
A focus on the RE-AIM factors of adoption, implementation, and sustainability of an IBCT self-management support system also addresses the larger issue of actionable information. With primary care already stretched beyond capacity to deal with care recommendations [5, 37, 38], adding additional assessment information will not solve the problem. Any additional information will need to be customized in ways that are compatible and integrated with practice flow, styles, priorities, and preferences to yield feasible, actionable outcomes. RE-AIM has previously been successfully applied to evaluate the impact of interactive technology approaches and clinic changes, providing an assessment of potential public health impact [20, 39, 40].
Many patients with chronic conditions experience major barriers to change related to ongoing co-morbid depression or disease-related distress, distinct conditions with different implications for care [41, 42]. For example, depression is about twice as prevalent among patients with diabetes compared to community samples, and ongoing distress related to managing a demanding chronic disease like diabetes has an average prevalence rate of 18% to 35% . Often, clinicians make recommendations for patients, only to see them not enacted because of feelings of hopelessness or being overwhelmed with the ongoing demands of chronic disease management. The delivery of actionable information must be tailored to the patient's capacity for change and the presence of emotional and distress-related barriers [41–43].
Characteristics of the Connection to Health system
The Connection to Health Patient Self-Management System is designed to deliver an array of tools to assist patients and providers in the assessment, monitoring, and management of a variety of health behaviors, psychosocial concerns, and chronic disease problems. The automated, web-based system uses engaging graphics, multimedia, and educational design techniques, and database-driven responses to provide three primary modules to address patient interaction and self-management--ongoing patient assessment, delivering summary self-management support reports, and providing recommendations for patients and healthcare teams. The assessment module uses brief evidence-based screening scales to assess behaviors (including diet, tobacco use, risky drinking, physical activity, and medication adherence) and chronic conditions (including obesity, diabetes, coronary heart disease, hypertension, hyperlipidemia, asthma, stress, and depression). The reporting module offers summary reports to both clinicians and patients that include assessment results, areas of concern, discussion options, and patient trends over time. The recommendations module provides clinician and patient with patient-tailored and prioritized suggestions for action, including development of goals and action plans in a variety of health behavior and psychosocial domains. Clinics or practices that adopt the system can customize the Connection to Health website through an administrative portal to reflect their local identity and resources (Figure 1). The system is adaptable for integration with electronic health records (EHRs) so that the results can be shared easily across clinical team members, and patient self-management support status can be monitored over time.
1. The clinic uses the administrative portal to enter initial patient contact information into the Connection to Health database. The system then sends an e-mail or letter to the patient with an embedded link to the secure, Health Insurance Portability and Accountability Act (HIPAA)-compliant website. The patient clicks on the link and is presented with a multimedia (audio and/or video) welcome message designed to engage the user and encourage participation, including a message from the practice to indicate that the program is part of the care provided by their clinician.
Prior to each regularly scheduled chronic disease or preventive healthcare office visit, patients are prompted to complete a brief online assessment through the Connection to Health system. This assessment can be conducted through a patient portal to the website through a home computer, practice computer kiosk or pen tablet computer, or a paper-and-pencil application that can be scanned into the system.
Once the patient has navigated through and completed the assessment module, the Connection to Health system uses validated algorithms to quickly score the assessments and display reports for both the patient and provider. The one-page patient report (example in Figure 2) can be viewed immediately through the patient portal or printed out hardcopy. It displays assessment results (including a history of recent assessments), areas of medical concern, and possible treatment options to discuss with the healthcare team. If the Connection to Health website is integrated with an EHR or laboratory reporting system, the patient report can also display selected, relevant laboratory results. The patient is encouraged to review the report, add her own notes or comments, and then have it sent or bring it to the next office visit or discussion with their clinician.
The physician report (Figure 3) contains much of the same information, but includes more details related to patient complexity, cardiovascular risk, health literacy and numeracy, and guideline concordant action recommendations. The goal of both reports is to provide an immediate, straightforward understanding of the patient's current health status; the self-management, psychosocial, and biologic areas of greatest patient concern; a prioritized list of items to discuss at the office visit; and an actionable set of self-management options and recommendations for flagged issues.
Tailored recommendations for action, based on the results of the assessments, are included in the patient and provider reports. For example, if the patient scored low in physical activity and consumed many high fat foods and had a high low-density lipoprotein (LDL) reading, the recommendations might include tips for beginning a conversation about eating patterns and a Connection to Health action plan for healthful eating and physical activity. The primary care team can review the patient and physician reports prior to the office visit, providing the primary care physician (PCP) with a concise set of assessment results and treatment options and tips for guiding the discussion with the patient.
The Connection to Health action plan module, available through the patient portal, provides a strategy for patient self-management that can be selected for use with patients who would respond to an interactive web-based action planning program and/or in situations where the practice does not have the time or appropriate staffing to complete the action planning process. This area of the website is derived from our series of successful interventions based upon problem-solving theory [44, 45]. This section offers engaging multimedia modules that guide the user through an action planning process for selected key health behaviors, including diet, exercise, medication adherence, smoking cessation, alcohol use, and depression/distress. These interactive modules facilitate patient selection of goals in any of these areas, and identification of benefits, barriers to success, and strategies for overcoming these barriers. The Connection to Health action plan module stores patient action plans and provides ongoing access to the plans by the healthcare team and the patient for self-monitoring and follow-up. Alternatively, the healthcare team may decide to provide intervention resources in person in the clinic or to refer the patient to a community resource (e.g., YMCA programs, voluntary associations, telephone help lines, or quit smoking cessation resources).
The Connection to Health System provides ongoing monitoring and prompts follow-up by both the patient and the practitioner. The self-monitoring component allows the patient to track their progress over time. Shortly before the patient is scheduled for another visit to the clinic or practice, he or she can be prompted to complete another set of brief assessments in advance of that visit and to review their history and progress.
Current Connection to Health measures
In choosing areas for screening and more in-depth assessment, we selected measures that address prevalent conditions or problems that have large public health impact, considered participant burden, and lead to actionable outcomes. Congruent with the recent policy recommendation from the Society of Behavioral Medicine http://www.sbm.org/policy/patient-reported_measures.pdf, we emphasized brief scales that were reliable, sensitive to change, appropriate for repeated administration, and age appropriate . As can be seen in Figures 1 and 2, Connection to Health currently includes assessments for depression, disease-related distress, medication adherence, smoking, physical activity, risky drinking, eating patterns, current stressors, and health literacy and numeracy. In addition, questions related to the patient's chronic diseases assess aspects of their management of those conditions. Additional file 1, Appendix 1 provides a brief summary of each instrument included in the Connection to Health assessment package.
Use of RE-AIM for Connection to Health development
We used the RE-AIM model [19, 33, 35] in developing the Connection to Health tool, by applying it to the goals of the PCMH. Table 1 summarizes how we addressed each of the RE-AIM elements.
Use of RE-AIM to develop Connection to Health PCMH tool
Ways dimension was used to enhance impact
Multiple input modalities; patient choice, panel report so can target those not participating
Practical, validated, actionable measures, evidence-based action suggestions. Patient choice to enhance autonomy. Expert system tailoring algorithms. Use of 5 A's, goal setting, and action planning problem solving.
Specifically designed to the support PCMH. Multiple options for customization of input, output, content, and recommended options. Panel reports for population management. Addresses HEDIS-related issues often missed.
Focus on efficiency, prompts to patient and healthcare team, done prior to visit, self-monitoring elements, engaging interface. Options for high and low eHealth literacy.
Setting Level: Feedback on HEDIS and PCMH criteria. Should enhance satisfaction and make visits more efficient and productive.
Patient Level: Should enhance continuity, patient-provider communication and satisfaction.
Connection to Health is designed to have high reach through several design features, including multiple modalities for data input and output. Patients can be provided with their choice of entry modality, and systems can be created to ensure that the entire patient panel of the practice is screened. Future iterations of Connection to Health will be designed with the capability to also accept data from automated telephone calls, cell phone data entry, a personal health record or EHR, and future data entry modalities.
Effectiveness is enhanced in multiple ways: use of practical, validated scales and measures [46–49]; links to evidence-based electronic and community resources; and patient choice at multiple steps in the process . Patient choice has been shown to be related to enhanced perceptions of autonomy support and improved outcomes . We also use expert system tailoring [51, 52] to select tailored intervention strategies based upon key behavioral and psychosocial factors. The system can easily be enhanced or modified overtime by adding in additional relevant local self-management support resources or other evidence-based links or information.
Connection to Health offers practices numerous incentives for adoption, providing techniques and options to assist practices in goals related to enhancing patient-centeredness, a primary goal of PCMH. Assessments can be completed before or after office visits, thus not taking any office time or interfering with patient flow. It addresses psychosocial issues such as distress and depression/anxiety, includes an efficient method for helping patients to prioritize their goals and questions, helps patients attend office visits well-prepared and engaged, and by doing so, saves practices time and increases efficiency. The use of Connection to Health also could assist the practice in meeting the standards for recognition as a PCMH and improve quality measures.
Being automated, Connection to Health ensures consistent delivery, accurate scoring, and immediate reporting of results. The administrative report feature enhances implementation by providing regular patient and panel-level reports at intervals specified by the practice and documents improvement over time.
Helping practices achieve, and be reimbursed for, higher performance on PCMH and quality measures should enhance maintenance. Maintenance at the patient level is enhanced by increased goal accomplishment, regular follow-up and feedback, and self-monitoring of individually targeted behaviors [53–55].
Initial provider reactions to Connection to Health
The initial version of the Connection to Health Patient self-management support was presented to a focus group of clinicians and staff from 10 family medicine practices working on implementation of the PCMH model. Field notes were taken by the two facilitators, and the participants also provided written comments using a structured format.
Feedback was very positive, providing important input regarding the assessment, the practice reports, and the potential implementation of the system in their practices. Comments highlighted the following issues:
1. Clinicians particularly liked that this system is designed to assist in focusing discussions of self-management issues between clinicians and patients and not to be a stand-alone system. They indicated that if the system was automated outside the practice, they believed that it would not be successful due to lack of reinforcement by the primary care clinicians.
2. Clinicians could be resistant because the system might cause them to feel separated from their patients. However, if the system is well-integrated within the practice, it will need to be done is a manner that minimizes the time commitment.
3. The flexibility and ability to customize the Connection to Health to fit needs, patient flows, and preferences of local clinics should aid adoption. Practices will have varying personnel and workflow that will necessitate different strategies for implementing the Connection to Health system at different points in patient flow and using different modalities in different practices.
4. Clinicians that have an EHR would like a seamless interface of the Connection to Health system with their system, while recognizing that will be a challenge.
5. Clinicians wanted to be shown how Connection to Health can be time-efficient
Most self-management support programs address a single disease or single behavior, and few are designed for primary care practices [51, 56]. In contrast, Connection to Health has broad applicability across diseases, prevention, multiple behaviors, and varied primary care settings for a wide range of adult patients. It can be accessed through several modalities and is appropriate for patients with diverse socioeconomic and educational backgrounds. It is designed to be integrated into primary care, creating efficiency while prompting informed provider-patient communication. Connection to Health should support the PCMH, create more informed and efficient office visits, and prompt and promote critical but often not completed follow-up support.
The primary purposes of this paper were to describe the Connection to Health system and how the RE-AIM framework was used proactively to develop it. Although controlled and comparative effectiveness studies are needed to determine the ultimate impact of the Connection to Health, use of implementation science models such as RE-AIM or other dissemination frameworks at the design stage [57, 58] should greatly facilitate greater uptake, implementation success, and long-term results. The Connection to Health is intentionally a work in progress, with iterative improvements to be made in the selection of measurement items and domains, patient and provider interfaces, and data input and output modalities.
Connection to Health is to our knowledge the only tool for addressing a wide variety of prevalent behavioral, psychosocial, and disease management problems managed in primary care. Time-efficient tools such as Connection to Health can help both patients and healthcare team members come to interactions more informed and prepared. This, in turn, should improve both outcomes and satisfaction [21, 25, 26, 59]. Finally, the panel management features of the Connection to Health should facilitate continuity of care and consistent follow-up, which is the element of care recommendations least often accomplished [60, 61].
Potential limitations include that the Connection to Health system is likely only appropriate for adult primary care patients, and not for children and adolescents (different measures would be needed). Currently, it is available only in English. Although computer administered, including automated skip patterns and individualized tailoring, it does not employ item response theory or formal computer-assisted testing procedures http://www.nihpromis.org/default.aspx. It is also possible that with repeated use over time that patients would begin to find the assessment process burdensome, and a Connection to Health quick-scan form may need to be developed for prevalent, well-defined subgroups of patients (e.g., overweight diabetes patients). The degree to which active follow-up with a patient within the PCMH model could overcome this limitation is an area ripe for investigation. Finally, although we found the RE-AIM model useful for planning and developing Connection to Health, other implementation science models could also have been used and RE-AIM does not explicitly address some issues such as stakeholder engagement. Readers interested in applying RE-AIM for program development and planning purposes should find the resources listed in Table 2 helpful for gaining a more complete understanding of the model and its implications.
Key RE-AIM Publications by Implementation Topic
Issue or Topic
Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: The RE-AIM framework. Am J Public Health 1999;89:1322-7 .
Use in Planning
Klesges LM, Estabrooks PA, Glasgow RE, Dzewaltowski D. Beginning with the application in mind: Designing and planning health behavior change interventions to enhance dissemination. Ann Behav Med 2005;29((Suppl)):66S-75S .
Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: The RE-AIM framework. Am J Public Health 1999;89:1322-7 .
Glasgow RE, Nutting PA, King DK, Nelson CC, Cutter G, Gaglio B, Rahm AK, Whitesides H. Randomized effectiveness trial of a computer-assisted intervention to improve diabetes care. Diabetes Care 2005 January;28(1):33-9 .
Glasgow RE, Nelson CC, Strycker LA, King DK. Using RE-AIM metrics to evaluate diabetes self-management support interventions. Am J Prev Med 2006;30(1):67-73 .
Primary Care Application
Glasgow RE. RE-AIMing research for application: Ways to improve evidence for family practice. Journal of the American Board of Family Practice 2006;19(1):11-9 .
Health Technology Applications
Glasgow RE, McKay HG, Piette JD, Reynolds KD. The RE-AIM framework for evaluating interventions: What can it tell us about approaches to chronic illness management? Patient Educ Couns 2001;44:119-27 .
Glasgow RE, Bull SS, Piette JD, Steiner J. Interactive behavior change technology: A partial solution to the competing demands of primary care. Am J Prev Med 2004;27(25):80-7 .
Jilcott S, Ammerman C, Sommers J, Glasgow RE. Applying the RE-AIM framework to assess the public health impact of policy change. Ann Behav Med 2007;34(2):105-14 .
Estabrooks PA, Bradshaw M, Dzewaltowski DA, Smith-Ray RL. Determining the impact of Walk Kansas: applying a team-building approach to community physical activity promotion. Ann Behav Med 2008 August;36(1):1-12 .
King DK, Glasgow RE, Leeman-Castillo B. RE-AIMing RE-AIM: Using the model to plan, implement, evaluate, and report the impact of environmental change approaches to enhance population health. Am J Public Health. 2010: 2076-2084 .
Future research should evaluate and document the actual use, time efficiency, multifaceted impact, reach or percent and characteristics of patients who can be assessed with it, and its actual implementation in primary care, using RE-AIM  or other implementation science models. In particular, comparative effectiveness research studies are indicated to determine, for example, if the Connection to Health is more cost-effective than alternatives, such as simple paper and pencil assessments followed by more traditional face-to-face interventions. Practical implications are that implementation science models, such as RE-AIM, should be employed throughout the design process to maximize impact.
The Colorado Health Foundation and Robert Wood Johnson Foundation provided funding that supported a portion of the planning and development of the Connection to Health Patient Self-management System.
Dr. Glasgow is now employed at the National Cancer Institute (NCI). This work was completed before he transitioned to the NCI and the opinions expressed do not necessarily reflect those of the NCI.
Division of Cancer Control and Population Sciences, National Cancer Institute
University of Colorado School of Medicine
Department of Family and Community Medicine, Diabetes Center, University of California, San Francisco, Parnassus Heights
Oregon Research Institute
Division of Pediatric Behavioral Health, National Jewish Health
Virginia Tech, Department of Human Nutrition, Foods and Exercise
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